干扰素β(IFNb)单克隆抗体

Monoclonal Antibody to Interferon Beta (IFNb)

IFNB1; IFN-B; IFB; IFF; IFNB; Interferon Beta 1 Fibroblast

  • 干扰素β(IFNb)单克隆抗体 产品包装(模拟)
  • 干扰素β(IFNb)单克隆抗体 产品包装(模拟)
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对IFNb的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别IFNb。

用法

免疫印迹:0.2-2µg/mL;1:500-5000
免疫组织化学:5-20µg/mL;1:50-200
免疫细胞化学:5-20µg/mL;1:50-200
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

赠品

相关产品

编号 适用物种:Rhesus monkey (Simian,恒河猴) 应用(仅供研究使用,不用于临床诊断!)
RPA222Si01 干扰素β(IFNb)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAA222Si01 干扰素β(IFNb)多克隆抗体 WB; IHC; ICC; IP.
MAA222Si21 干扰素β(IFNb)单克隆抗体 WB; IHC; ICC; IP.
SEA222Si 干扰素β(IFNb)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA222Si 干扰素β(IFNb)等多因子检测试剂盒(流式荧光发光法) FLIA Assay for Antigen Detection.

参考文献

杂志 参考文献
20 Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway [PubMed: 21355876]
Journal of General Virology Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKε and DDX3. [Sgm: 9182080]
Biochemical and Biophysical Research Communications Impaired TLR3/IFN-β signaling in monocyte-derived dendritic cells from patients with acute-on-chronic hepatitis B liver failure: Relevance to the severity of liver damage [ScienceDirect: S0006291X09019822]
PLoS One Intact Type I Interferon Production and IRF7 Function in Sooty Mangabeys [PubMed: PMC3757038]
PLoS Neglected Tropical Diseases Innate Immune Response to Rift Valley Fever Virus in Goats [PubMed: PMC3335883]
BioMed Research International Low pH Environmental Stress Inhibits LPS and LTA-Stimulated Proinflammatory Cytokine Production in Rat Alveolar Macrophages [Pubmed: 24288685]
Vet Microbiol. An attenuated EIAV strain and its molecular clone strain differentially induce the expression of Toll-like receptors and type-I interferons in equine monocyte-derived macrophages. [Pubmed: 23850441]
Food and Chemical Toxicology Scoparone attenuates d-galactosamine/lipopolysaccharide-induced fulminant hepatic failure through inhibition of toll-like receptor 4 signaling in mice [Pubmed: 23535186]
Veterinary immunology and immunopathology Experimental model of equine alveolar macrophage stimulation with TLR ligands [Pubmed: 23815824]
American journal of respiratory cell and molecular biology Training Modifies Innate Immune Responses in Blood Monocytes and in Pulmonary Alveolar Macrophages [Pubmed: 24502337]
FEBS Lett. Mannan binding lectin attenuates double-stranded RNA-mediated TLR3 activation and innate immunity [Pubmed:24530528]
Veterinary Research Infection of equine monocyte-derived macrophages with an attenuated equine infectious anemia virus (EIAV) strain induces a strong resistance to the infection by a virulent EIAV strain [Pubmed:25106750]
PLOS Neglected Tropical Diseases MicroRNA-30e* Suppresses Dengue Virus Replication by Promoting NF-κB–Dependent IFN Production [Pubmed:25122182]
Veterinary Research The innate immune response of equine bronchial epithelial cells is altered by training [Pubmed:25595212]
molecular and celluar biology SOCS3 Drives Proteasomal Degradation of TBK1 and Negatively Regulates Antiviral Innate Immunity [PubMed: 25939384]
Arch Virol Analysis of cytokine production in a newly developed canine tracheal epithelial cell line infected with H3N3 canine influenza virus [PubMed: 25797196]
J Complexes of DNA with the Antimicrobial Peptide LL37 Augment NK Cell Functions by Inducing Type I Interferon Production from Circulating Monocytes and Plasmacytoid Predendritic Cells [PubMed: 26258404]
Virus PKR activation enhances replication of classical swine fever virus in PK-15 cells [PubMed: 25899421]
PLoS One siRNA Targeting the 2A pro Genomic Region Prevents Enterovirus 71 Replication In Vitro [Pubmed:26886455]
Scientific Reports Cellular uptake of exogenous calcineurin B is dependent on TLR4/MD2/CD14 complexes, and CnB is an endogenous ligand of TLR4 [Pubmed:27090571]
Front Microbiol Innate Immune Responses in ALV-J Infected Chicks and Chickens with Hemangioma In Vivo [Pubmed:27252695]
Canadian Journal of Physiology and Pharmacology Chloroquine attenuates lipopolysaccharide-induced inflammatory responses through upregulation of USP25. [pubmed:28134560]
International Journal of Molecular Medicine Effects of IRF1 and IFN-β interaction on the M1 polarization of macrophages and its antitumor function [pubmed:27176664]
International Journal of Clinical and Experimental Pathology Host miR-146a promotes replication of human cytomegalovirus by suppressing type I IFN response in MRC-5 cells [files:ijcep0036479.pdf]
Poultry Science ALV-J strain SCAU-HN06 induces innate immune responses in chicken primary monocyte-derived macrophages [pubmed:27486255]
Journal of Virology Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized inPlasma and Milk in Chronically Infected African Green Monkeys. [pubmed:]
Biochemical and Biophysical Research Communications MicroRNA-548j inhibits type I interferon production by targeting ZBTB11 in patients with chronic hepatitis B [pubmed:28342861]
Virology The down-regulation of casein kinase 1 alpha as a host defense response against infectious bursal disease virus infection [pubmed:28988058]
EMBO Journal Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1‐caspase‐1 axis [Pubmed:30065070]
Toxicology and applied pharmacology Bisphenol A induced male germ cell apoptosis via IFNβ-XAF1-XIAP pathway in adult mice [Pubmed:30017639]
Archives of Virology MAVS induces a host cell defense to inhibit CSFV infection [Pubmed:29556776]
Journal of virology Inhibition of DNA-sensing pathway by Marek's disease virus VP23 protein through suppression of interferon regulatory factor 7 activation [Pubmed: 30518647]
Veterinary Immunology and Immunopathology Molecular cloning and functional characterization of porcine 2′, 5′-oligoadenylate synthetase 1b and its effect on infection with porcine reproductive and respiratory?… [Doi: 10.1016/j.vetimm.2019.01.003]
Science Signaling HIPK2 is necessary for type I interferon–mediated antiviral immunity [Doi: 10.1126/scisignal.aau4604]
INTERNATIONAL MEDICAL RESEARCH Evaluation of serum interferons in patients with age-related macular degeneration [Pubmed: 31007694]
Veterinary Immunology and Immunopathology Differential expression of type I interferon mRNA and protein levels induced by virulent Marek's disease virus infection in chickens []
International journal of biological macromolecules Porcine FcγRIIb mediated PRRSV ADE infection through inhibiting IFN-β by cytoplasmic inhibitory signal transduction [Pubmed: 31284005]
Journal of virology Marek's Disease Virus RLORF4 Inhibits Type I Interferon Production by Antagonizing NF-κB Activation [Pubmed: 31243133]
The Journal of Latvian Academy of Sciences Serodiagnosis of Human Bocavirus 1 Infection among Hospitalised Children with Lower Respiratory Tract Infection in Latvia []
Cancer Medicine The immunostimulatory effects and pro‐apoptotic activity of rhCNB against Lewis lung cancer is mediated by Toll‐like receptor 4 [Pubmed: 31218844]
FASEB Journal Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF 3 ubiquitination through recruiting OTUB 1 []
PLOS Pathogens Avian oncogenic herpesvirus antagonizes the cGAS-STING DNA-sensing pathway to mediate immune evasion [Pubmed: 31539404]
Autophagy Induction of autophagy and suppression of type I IFN secretion by CSFV [Pubmed: 32160078]
MOLECULAR IMMUNOLOGY BVDV-1 induces interferon-beta gene expression through a pathway involving IRF1, IRF7, and NF-κB activation [Pubmed: 33053462]
Autophagy LDHB inhibition induces mitophagy and facilitates the progression of CSFV infection [Pubmed: 32924761]
Arch Virol . Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway [Pubmed: 32532134]
Virulence Determination of antiviral action of Long Non-coding RNA loc107051710 During Infectious Bursal Disease Virus Infection due to Enhancement of Interferon … []
bioRxiv Transferrin-dependent crosstalk between the intestinal tract and commensal microbes contributes for immune tolerance []
Res Vet Sci Open reading frame 5 protein of porcine circovirus type 2 induces RNF128 (GRAIL) which inhibits mRNA transcription of interferon-β in porcine epithelial cells [34416463]
Eur J Immunol Anti‐IFN‐α/‐ω neutralizing antibodies from COVID‐19 patients correlate with downregulation of IFN response and laboratory biomarkers of disease severity [Pubmed:35419822]
ResearchSquare Chicken Intestinal Microbiota Modulation of Resistance to Nephropathogenic Infectious Bronchitis Virus Infection Through IFN-I []
留言咨询