肿瘤坏死因子β(TNFb)活性蛋白

Active Tumor Necrosis Factor Beta (TNFb)

LT; LTA; TNF-B; TNFSF1; Tumor Necrosis Factor Ligand Superfamily Member 1; Lymphotoxin Alpha

  • 肿瘤坏死因子β(TNFb)活性蛋白 产品包装(模拟)
  • 肿瘤坏死因子β(TNFb)活性蛋白 产品包装(模拟)
  • APA134Hu01.jpg Figure. SDS-PAGE
  • 肿瘤坏死因子β(TNFb)活性蛋白 WB图
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

活性实验

TNF-β, a member of the tumor necrosis factor family, is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells. The biological effects of TNF-β are very similar to TNF-α, due to the similarity of molecular structure and the receptors. As reported, TNF-β could inhibit the proliferation and induce necrosis of A549 cells, and the concentration of IL-1β in cell supernatant will increase after stimulation. Therefore, A549 cells were incubated in DMEM with TNF-β (10ng/mL) for 8h, 24h, 48h, 72h, then cells were observed by inverted microscope and IL-1β was detected in the cell supernatant by ELISA .
Cell necrosis after incubation with TNF-β(10ng/mL) for 72h was shown in Figure 1.

The production of IL-1β after incubation with TNF-β (10ng/mL) for 8h is shown in Table 1.

用法

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

储存

避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

相关产品

编号 适用物种：Homo sapiens (Human，人) 应用(仅供研究使用，不用于临床诊断！)
APA134Hu01 肿瘤坏死因子β(TNFb)活性蛋白 Cell culture; Activity Assays.
RPA134Hu01 肿瘤坏死因子β(TNFb)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAA134Hu01 肿瘤坏死因子β(TNFb)多克隆抗体 WB; IHC; ICC; IP.
MAA134Hu22 肿瘤坏死因子β(TNFb)单克隆抗体 WB; IHC; ICC; IP.
MAA134Hu21 肿瘤坏死因子β(TNFb)单克隆抗体 WB; IHC; ICC; IP.
SEA134Hu 肿瘤坏死因子β(TNFb)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA134Hu 肿瘤坏死因子β(TNFb)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.

参考文献

杂志 参考文献
Journal of Applied Physiology Simvastatin attenuates sympathetic hyperinnervation to prevent atrial fibrillation during the postmyocardial infarction remodeling process [PubMed: 22984252]
Journal of Translational Medicine Effectiveness of pure argon for renal transplant preservation in a preclinical pig model of heterotopic autotransplantation [Pubmed:26847569]
International Journal of Stem Cell Research and Transplantation Protective Role of Bone Marrow Derived Mesenchymal Stem Cells-Conditioned Medium in the Infarcted Myocardium: The Potential Role of Selected Cytokines [IJST-2328-3548-04-803]
Probiotics Antimicrob Proteins Effect of Multi-Microbial Probiotic Formulation Bokashi on Pro-and Anti-Inflammatory Cytokines Profile in the Serum, Colostrum and Milk of Sows, and in a … [Pubmed:29305686]
Parasites & Vectors Fasciola gigantica excretory-secretory products (FgESPs) modulate the differentiation and immune functions of buffalo dendritic cells through a mechanism … [Pubmed: 32680553]
Microbiome changes in patients with chronic heart failure with preserved ejection fraction correlate with fibrosis markers: Description of a Russian cohort []
BMC MUSCULOSKELETAL DISORDERS Elevated lymphotoxin-¦Á (TNF¦Â) is associated with intervertebral disc degeneration [33441130]
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