组蛋白H4(H4)重组蛋白

Recombinant Histone H4 (H4)

  • 编号RPA289Mi02
  • 物种Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，猫), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，猪), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，马) 相同的名称，不同的物种。
  • 来源原核表达
  • 宿主E.coli
  • 内毒素水平<1.0EU/µg(LAL法测定)
  • 亚细胞定位分泌, 染色体
  • 预测分子量41.3kDa
  • 实际分子量42kDa(差异分析请参阅说明书)
  • 片段与标签Ser2~Gly103 with N-terminal His and GST Tag
  • 缓冲液成份20mM Tris, 150mM NaCl缓冲液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
  • 性状冻干粉
  • 纯度> 90%
  • 等电点11.9
  • 应用 Positive Control; Immunogen; SDS-PAGE; WB.
    如果需要有生物活性的蛋白，请参见活性蛋白。
  • 下载 英文说明书   中文说明书
  • 规格 10µg50µg 200µg 1mg 5mg
  • 价格 ¥ 984 ¥ 2460 ¥ 4920 ¥ 14760 ¥ 36900
  • 欲了解实际交易价格和更多情况，请与当地经销商联系!
  • 组蛋白H4(H4)重组蛋白 产品包装(模拟)
  • 组蛋白H4(H4)重组蛋白 产品包装(模拟)
  • 组蛋白H4(H4)重组蛋白 Figure . Gene Sequencing (extract)
  • RPA289Mi02.jpg Figure. SDS-PAGE
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

序列

用法

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

储存

避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

相关产品

编号 适用物种：Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，猫), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，猪), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，马) 应用(仅供研究使用，不用于临床诊断！)
RPA289Mi02 组蛋白H4(H4)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA289Mi01 组蛋白H4(H4)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAA289Mi02 组蛋白H4(H4)多克隆抗体 WB; IHC; ICC; IP.
PAA289Mi01 组蛋白H4(H4)多克隆抗体 WB; IHC; ICC; IP.
SEA289Mi 组蛋白H4(H4)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
HEA289Mi 组蛋白H4(H4)检测试剂盒(酶联免疫吸附试验法,高敏型) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA289Mi 组蛋白H4(H4)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.

参考文献

杂志 参考文献
PLoS One. N-Acetyl-Heparin Attenuates Acute Lung Injury Caused by Acid Aspiration Mainly by Antagonizing Histones in Mice [Pubmed:24816808]
Crit Care. Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation [Pubmed:25260379]
Biomed Res Int A Novel Anti-Histone H2 Monoclonal Antibody, SSV Monoclonal Antibody, Improves Lung Injury and Survival in a Mouse Model of Lipopolysaccharide-Induced Sepsis-Like Syndrome [PubMed: 25649891]
Journal of Viral Hepatitis Patients with HBV-related acute-on-chronic liver failure have increased concentrations of extracellular histones aggravating cellular damage and systemic inflammation [pubmed:27660136]
Cell Death & Disease Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis [Pubmed: 30778043]
Respir Res Histone H4 induces heparan sulfate degradation by activating heparanase in chlorine gas-induced acute respiratory distress syndrome [Pubmed:35073921]
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